We aimed at restoring the sensibility to Platinum-based drugs through a direct inhibition of TS without affecting TS-mRNA interaction that leads to TS protein synthesis modulation/alteration Thus, novel non-cross resistant chemotherapeutic drugs are urgently needed in this disease. LIGHTS project can support the discovery of new potential anticancer drugs against cross resistant Pt-based drugs with non-cross resistant profiles. For dissemination higlights please visit the following address http://www.scifar.unimore.it/on-line/Home/Personale/articolo2002005.html |